Phenoscanner gwas
Web1. máj 2024 · In a bioinformatics analysis for novel associations, we used Phenoscanner to query whether genome-wide significant SNPs were associated with DNA methylation, 34, 35 metabolite levels, or protein levels from genome-wide studies at genome-wide significance (p<5 × 10 −8) in other GWAS. Web21. feb 2024 · ScienceOpen: research and publishing network For Publishers. Discovery Metadata Peer review Hosting Publishing
Phenoscanner gwas
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WebBackgroundThe causal association between coffee consumption and the risk of OA is limited. This study was conducted to identify the potential causal effects of coffee consumption on total, knee, hip, and self-reported OA.MethodsGenome-wide association studies (GWAS) of OA were derived from the UK Biobank, comprising 50,508 participants … Web4. dec 2024 · rs145163454 1:169090748 - - - Antithrombotic agents Environmental GWAS_ATLAS 31015401 rs145163454 1:169090748 rs2227246 1:169208179 1 Benign …
Web15. apr 2024 · Alzheimer’s disease (AD) represents the most common form of dementia (1).Epidemiological studies have found that the earliest pathological event in disease progression is reduced cerebral blood flow (1).Hypertension is one of the most common conditions that degrade cerebral circulation, and it has been found that prolonged high … WebThe GUGC GWAS comprised more than 140 000 individuals of European ancestry. 20 Twenty-eight SNPs associated with serum UA levels were selected from GUGC GWAS, which were identified to be of genome-wide significance ( P <5×10 −8) in the combined sample (discovery sample + replication sample).
WebPhenoScanner: a database of human genotype-phenotype associations Bioinformatics 2016 Conventional protein kinase C isoforms differentially regulate ADP- and thrombin-evoked Ca²⁺ signalling in... WebBackground Obstructive sleep apnea (OSA) has shown to be associated with an increased risk of atrial fibrillation in observational studies. Whether this association reflect causal effect is still u...
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Web18. apr 2024 · We also looked up three databases (Ensembl, GWAS Catalog, and PhenoScanner) for any potential associations of the selected SNPs with other risk factors (confounders) of mental disorders identified by previous MR studies. A specifically confirmed confounder investigated among different MR studies should present consistent … how to declare pointer variableWeb全基因组关联分析(GWAS)是科研领域近几年一直很火的名词,也发了很多高水平的论文。 这个数据库是中科院基因组所大数据中心开发的GWAS整合数据库,包括水稻、玉米、高 … the moebius factor mapWeb10. sep 2024 · Using PhenomeXcan results, we provide examples of novel and underreported genome-to-phenome associations, complex gene-trait clusters, shared … the moe hotelWeb1 Introduction. Cardiometabolic diseases refer to a clinical syndrome primarily caused by metabolic disorders, with atherosclerotic cardiovascular disease as the main manifestation, except for structural cardiovascular pathologies, arrhythmias and cardiomyopathies ().There is an explicit causal relationship between metabolic abnormalities and cardiovascular … the moebius factor brutalWeb24. aug 2024 · Phenoscanner tests were the instrumental variants (IVs), homocysteine was the exposure, and BRCA, PrCa, and RCC were the outcomes. Single-nucleotide … how to declare public variable in vb.netWebMendelian randomisation uses genetic variation as a natural experiment toward investigate the causal relations between potential modifiable gamble factors and health outcomes in observational data. As with all using approaches, findings with Mendelian randomisation studies depend on specific assumption. We provide explanations is the resources … how to declare protected variable in pythonWeb孟德尔随机化分析018. 如何5分钟快速转换rsid--无论ukb、芬兰、任意GWAS都可以. 孟德尔随机化,MRPRESSO结果规整, list转data.frame. 孟德尔随机化,R::PhenoScanner, 混杂因素 ... how to declare prototype for function in c