WebNational Center for Biotechnology Information WebTULP3 interacts with the IFT-A complex. To gain insight into the molecular function of TULP3, we generated localization and tandem affinity purification (LAP)-tagged stable clonal cell lines in telomerase immortalized hTERT RPE-1 (RPE) cells (Nachury et al. 2007).We identified the TULP3-associated proteins by tandem affinity purification followed by mass …
IFT52 Gene - GeneCards IFT52 Protein IFT52 Antibody
Web11 nov. 2016 · IFT protein complexes have been distinguished into complex A and complex B, containing ∼20 IFT proteins in Chlamydomonas (Fort and Bastin, 2014). … Web1 jul. 2024 · The stable IFT-B core complex is known as IFT-B1 (IFT88, -81, -74, -70, -52, -46, -27, -25, and -22) interacting with the second subcomplex known as IFT-B2 (IFT172, … houghton lake mi homes for sale
Assembly and stability of IFT-B complex and its function in …
Web20 aug. 2024 · The large MDa IFT-B complex constitutes the backbone of polymeric IFT trains that carry ciliary cargo between the cilium and the cell body. Currently, high-resolution structures are only available for smaller IFT-B sub-complexes leaving >50% of the IFT-B complex structurally uncharacterized. Web1 nov. 2024 · Dynein-2 is omitted for clarity. IFT-B repeats every 6 nm along the long axis of the train, whereas IFT-A repeats every 11 nm [28]. (B) Sub-tomogram averages of IFT-A ... Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal. Mol. Biol. Cell, 28 (2024 ... Web17 sep. 2024 · The intraflagellar transport (IFT) machinery, which includes the IFT-A and IFT-B complexes, mediates bidirectional trafficking of ciliary proteins. In addition to these complexes, the BBSome, which is composed of eight subunits that are encoded by the causative genes of Bardet-Biedl syndrome (BBS), … link for new army email