Granulophysin
Webgranulophysin (uncountable) (biochemistry) A membrane protein sometimes present in blood platelets WebCD63 molecule. Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and ...
Granulophysin
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WebJun 1, 1997 · Granulophysin labels the dense granule membrane (D) but not the α-granules (A). Gp Ib is found essentially along the plasma membrane (pm). The OCS and some α-granules (A) are occasionaly labeled. It also double-labels the dense granule membrane (D) identified by the presence of granulophysin. (Original magnification × … WebThe H5C6 monoclonal antibody specifically binds to CD63. CD63 is a 53 kDa, type III lysosomal glycoprotein, expressed on activated platelets, monocytes and macrophages. This molecule is also referred to in the literature as LIMP, gp55, melanoma-associated antigen ME491, Pltgp40, LAMP-3 and is a member of the tetraspan transmembrane 4 …
WebTarget Information. CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. CD63 is also present in the plasma membrane, usually following cell activation. Hence, CD63 has become a widely used basophil activation …
WebGranulophysin (CD63) is a protein in the tetraspanin group and is found in, among others, the dense granules and the α-granules of platelets [139,140], as well as the azurophilic granules of ... WebJun 15, 2000 · Arrowheads indicate granulophysin (10-nm gold particles), and arrows indicate α-granule marker von Willebrand factor (5-nm gold particles). Both proteins can be found within the same MVB, but they are segregated from each other in distinct microvesicles. Granulophysin is also preferentially associated with the limiting …
WebJul 1, 1992 · We recently reported the characterization of a platelet granule membrane protein of molecular weight (mol wt) 40,000 called granulophysin (Gerrard et al: Blood …
WebJun 15, 2000 · It can only be identified by GPIb-specific expression on its plasma membrane (pm). Granulophysin labels the membrane of vacuolar structures, which can be … how do i download the barclays appWebView application images and datasheets for 1333 anti Granulophysin Antibody antibodies from 38 leading antibody suppliers, plus reviews and the top related antibodies how much is purviewWebAnti-MLA1 antibody, anti-TSPAN30 antibody, anti-CD63 antigen antibody, anti-Granulophysin antibody, anti-Lysosomal-associated membrane protein 3 antibody, anti-LAMP-3 antibody, anti-Melanoma-associated antigen ME491 antibody, anti-OMA81H antibody, anti-O: Produktbeschreibung. Mouse monoclonal antibody to CD63: how much is purple heart stamp worthWebSep 1, 1992 · Recently the platelet protein granulophysin, specific to the membrane of the DG, has been described and defined through the use of monoclonal antibodies … how much is purple heart wood worthWebprotein called granulophysin ( 15, 16), which is decreased in the Hermansky-Pudlak syndrome (15, 17). Ourresults thus providethefirstidentification … how do i download the hbomax appWebNational Center for Biotechnology Information how much is purple kushWebAnti-CD63 (LAMP3), clone ME491, Cat. No. MABF2159, is a mouse monoclonal antibody that detects CD63 antigen and has been tested for use in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), and Western Blotting. Immunohistochemistry (Paraffin) Analysis: A 1:250 dilution from a representative lot … how much is pvc fence installed